In IVF treatment, the two most important factors affecting the success rate of IVF are the woman's age and low egg reserve, i.e. low AMH level.
The AMH hormone, which indicates low egg reserve, is secreted from preantral egg cells, called precursor egg cells, in the ovarian tissue of women.
Some of these cells are selected before the menstrual period, start to grow and then one of them becomes dominant and ovulation occurs. This process takes approximately 60-70 days.
The low egg reserve hormone AMH starts to decrease as the number of these precursor egg cells decreases. When it falls below a certain level, menopause begins in women.
The low egg reserve hormone AMH remains constant for a month, regardless of the menstrual period. Therefore, the level of this hormone can be measured at any time outside the menstrual period.
If there is low egg reserve (AMH) and pregnancy does not occur despite 6 months of unprotected intercourse over 35 years of age, IVF treatment is the most important alternative.
In younger women, if there is 1 year of unprotected intercourse and the AMH level is below 1.1 ng/ml, it will be useful to recommend IVF treatment.
The low egg reserve hormone AMH decreases with age. In addition, if the blood sample taken while measuring the AMH hormone is stored outside for a long time or depending on the difference in the laboratory kits, it may vary slightly.
The low egg reserve hormone AMH can be measured at any time during menstruation.
One of the most important issues in the success of IVF in women with low AMH is the number of eggs and the age of the woman.
On the 2nd or 3rd day of the menstrual period, the number of eggs in the ovarian tissue and the low egg reserve (AMH) test are evaluated together by ultrasound. In these patients, the age of the woman affects the result the most. The most important issue in the success of the treatment of these patients is the experience of the physician who will perform the treatment and the type of treatment applied.
In IVF treatment in women with low egg reserve (AMH),egg quality is lower than in patients with normal egg reserve. Therefore, it is important to apply supportive treatments to improve the egg quality of these patients in terms of IVF success.
These treatments can be in the form of nutritional supplements called antioxidants, growth hormone or male hormone applications.
Low egg reserve means an AMH level below 1.1 ng/ml. However, some women may have a lower number of eggs on ultrasound even if their AMH levels are higher. This is why AMH or egg count alone is not enough to determine low egg reserve. The most accurate way is to evaluate these two parameters together.
The most popular method applied today to increase AMH in low egg reserve is Prp. Although there are scientific studies showing an increase in egg reserve test AMH with Prp treatment, especially in Greece and Turkey, it has not yet been clearly proven.
Dear couples and readers, you can review our topics below for all your questions about IVF treatment and infertility and answers to any questions you may have. All you wonder about IVF, infertility and gynecological diseases...
In vitro fertilization, also known as in vitro fertilization, is the process of combining eggs and sperm in a laboratory environment and transferring the resulting embryo to the mother's uterus.
When success is expressed as pregnancy rate, it is generally known to be inversely proportional to increasing age. As the woman's age increases, the success rate of IVF decreases.
The use of PRP in the field of reproductive medicine has increased and become popular. Low ovarian reserve, menopause and endometrium (inner sheath of the uterus) have become new areas where PRP is used.